Abstract: This study is aimed to screen the excellent Vitis vinifera‘Cabernet Franc’clone with higher contents of flavanol and anthocyanin so as to provide a theoretical basis for the breeding of wine grapes in Penglai regions. Cabernet Franc and 3 grapevine clones（214，327，623）in Penglai region were selected as the test samples to determine the contents of the total phenol，total tannin，and total anthocyanidins in grape skin and seeds through spectrophotometer method. In the meantime，contents of phenolic acids，flavonols，flavanols，anthocyanins，and resveratrol were measured by high performance liquid chromatography（HPLC）. The results showed that flavanol was the main type of monomeric phenols and the content of catechin was the highest. The malvidin-3-O-glucoside was the main anthocyanin. Under the same cultivation and management conditions as well as the natural conditions，significant differences were found in phenolic substances among different clones of Cabernet Franc. In addition，obvious differences were observed in the same clones of different cultivation years. Thereinto，the total phenolic content in the skin and seeds，the total tannin，and flavanol in the seed，as well as the phenolic acid and monomer anthocyanin content in the skin and seed were significantly higher in the 623 clone than other grape clones，indicating that the performance of clone 623 was better than that of the clones and Cabernet Franc.

Key words: grape, clone, flavonols, flavanols, anthocyanin